The world premiere of Dan’s new video game opera PermaDeath takes place at Boston’s Emerson Cutler Majestic Theater from September 27-29. PermaDeath is the “intrepid and artistically ambitious” (Opera magazine) Jacobs’s most technologically sophisticated work to date, requiring a host of technical collaborators, and focuses on a central character suffering from ALS, which required an entirely different kind of collaboration and research. The libretto was co-written with Jacobs’s son, Pirate Epstein, founder of the video game company SqueePlay and a former New England Halo champion. New York-based opera director Sam Helfrich, who helmed the first…